Chronic ethanol (EtOH) feeding induces subset loss and hypo-responsiveness in multiple skin T cell populations

17 Feb
2012

Alcoholism is associated with cutaneous immune deficiency and while the basis for this is largely unknown, the sensitivity of skin immune cells to EtOH has been clearly demonstrated. Murine models of alcoholism have shown that EtOH reduces skin dendritic cell (DC) numbers and compromises their migratory capacity following skin sensitization.

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Chronic ethanol (EtOH) feeding induces subset loss and hypo-responsiveness in multiple skin T cell populations

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