IntroductionTumor necrosis factor-alpha (TNF-alpha) is a proinflammatory cytokine which plays a central role in the pathogenesis of rheumatoid arthritis (RA).
This study indicates that Mesoglow® and IAL System® are equally effective in achieving short‐term correction of NLFs, but the longevity of their effects is limited. (Source: International Journal of Dermatology)
ConclusionsAlthough few studies tested the effects of activated PRP on hair growth, this research provides support for possible clinical application of autologous PRP and its secretory factors for promotion of hair growth. (Source: Dermatologic Surgery)
Conclusions. Combined application of nadifloxacin with any of the other four topical anti‐acne products did not lead to substantial intolerance reactions compared with the effects after application of the products alone.
Alcoholism is associated with cutaneous immune deficiency and while the basis for this is largely unknown, the sensitivity of skin immune cells to EtOH has been clearly demonstrated. Murine models of alcoholism have shown that EtOH reduces skin dendritic cell (DC) numbers and compromises their migratory capacity following skin sensitization.
AbstractBacteria colonizing chronic wounds often exist as biofilms, yet their role in chronic wound pathogenesis remains unclear. Staphylococcus aureus biofilms induce apoptosis in dermal keratinocytes, and given that chronic wound biofilms also colonize dermal tissue, it is important to investigate the effects of bacterial biofilms on dermal fibroblasts
Authors: Romoser AA, Figueroa DE, Sooresh A, Scribner K, Chen PL, Porter W, Criscitiello MF, Sayes CM Abstract There are many efforts in understanding the effects of nanoparticles on cell viability and metabolism, however, not much is known regarding the distinct molecular mechanisms of inflammation and cellular stress using low dosing concentrations. To address this gap in the literature, we utilized a novel experimental design that specifically probes the effects of a panel of commonly studied engineered nanomaterials along immunomodulatory pathways, including NF-κB. The panel of particles selected for this study included quantum dot nanocrystals, titanium dioxide, hydroxylated fullerenes, and silver nanoparticles
In this study, we examined the effects of a novel NO-releasing nanoparticle technology on wound healing in mice. The results show that the NO nanoparticles (NO-np) significantly accelerated wound healing
SynopsisCoenzyme Q10 (CoQ10) is a well known anti‐oxidant, and has been used in many skin care products for anti‐ageing purpose. However, the molecular mechanisms of CoQ10 function in skin cells are not fully understood. In this paper, we compared the effects of CoQ10 on primary human dermal fibroblasts from three individuals, including adult.
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