Posts Tagged ‘experimental’
Authors: Jepps OG, Dancik Y, Anissimov YG, Roberts MS Abstract Many drugs are presently delivered through the skin from products developed for topical and transdermal applications.
Conclusion
Hair‐inducing ability of human dermal papilla cells cultured under Wnt/β‐catenin signalling activation
15, Mar 2012This study may provide valuable information to establish a culture method of human DPCs for cell‐based therapy. (Source: Experimental Dermatology)
- In: Health News
- Tags: culture-method, experimental, provide-valuable, study, study-may
Lack of irritative potential of nadifloxacin 1% when combined with other topical anti‐acne agents
18, Feb 2012Conclusions. Combined application of nadifloxacin with any of the other four topical anti‐acne products did not lead to substantial intolerance reactions compared with the effects after application of the products alone.
- In: Health News
- Tags: acne-products, clinical, combined, effects, experimental, four-topical, products, reactions-compared, the-products, topical
We report the case of a 5â€monthâ€old male infant who presented with slowly progressive linear atrophic skin lesions. The histological findings showed evidence of dermal hypoplasia.
- In: Health News
- Tags: case, clinical, early-sign, experimental, father-had, findings-showed, gene-identified, gnas, infant, linear-atrophic, months, php, skin-lesions, the-infant
Infantile systemic hyalinosis associated with a putative spliceâ€site mutation in the ANTXR2 gene
2, Feb 2012We report an Indian child with ISH in whom we identified a homozygous acceptor splice site mutation, IVS2–4G> A. In silico analysis of this sequence showed that it changed predicted cryptic splicing, leading to outâ€ofâ€frame transcripts and little, if any, functional protein. Mutations in the ANTXR2 gene can also cause juvenile hyaline fibromatosis (JHF)
- In: Health News
- Tags: antxr2, based-prenatal, clinical, cryptic-splicing, dna, experimental, gene-makes, indian, ish, jhf, sequence, splice-site
Hair‐inducing ability of human dermal papilla cells cultured under Wnt/β‐catenin signaling activation
27, Jan 2012This study may provide valuable information to establish a culture method of human DPCs for cell‐based therapy. (Source: Experimental Dermatology)
- In: Health News
- Tags: culture-method, experimental, provide-valuable, study, study-may
A Fibrocontractive Mechanochemical Model of Dermal Wound Closure Incorporating Realistic Growth Factor Kinetics.
13, Jan 2012Authors: Murphy KE, Hall CL, Maini PK, McCue SW, McElwain DL Abstract Fibroblasts and their activated phenotype, myofibroblasts, are the primary cell types involved in the contraction associated with dermal wound healing. Recent experimental evidence indicates that the transformation from fibroblasts to myofibroblasts involves two distinct processes: The cells are stimulated to change phenotype by the combined actions of transforming growth factor β (TGFβ) and mechanical tension. This observation indicates a need for a detailed exploration of the effect of the strong interactions between the mechanical changes and growth factors in dermal wound healing
