Skin is an immune system favorite. There is plenty of rationale for this favoritism. Skin serves as an environment-sensing organ for the immune system
Abstract: Glycyrrhizic acid (GA), a triterpenoid saponin glycoside from the roots and rhizomes of licorice is used in traditional and modern medicine for the treatment of numerous medical conditions including skin diseases and beauty care product.
Authors: Nakajima H, Ezaki Y, Nagai T, Yoshioka R, Imokawa G Abstract We recently reported that overexpression of the elastase NEP (neutral endopeptidase) by fibroblasts plays a pivotal role in the mechanism of UVB-induced skin wrinkling by degrading dermal elastic fibres. Since UVB does not penetrate to the dermis, we hypothesized that factors secreted by UVB-exposed keratinocytes in the epidermis trigger fibroblasts in the dermis to increase their expression of NEP which then degrades the elastic fibres. In the present study, we characterized the epithelial-mesenchymal interaction between keratinocytes and fibroblasts which leads to increased expression of NEP
The aqueous extracts of Citrus unshiu peel containing flavonoid glycosides was used as co‐substrate with Schizophyllum commune mycelia producing β‐glucosidase and its biological activities were studied. β‐glucosidase‐produced S. commune mycelia converted the glycosides (narirutin and hesperidin) into aglycones (naringenin and hesperetin).
Celebrity Dirty Laundry Cameron Diaz Destroyed By Cosmetic Surgery Gone Wild (Photo) Celebrity Dirty Laundry This appears to be the result of Restylane or Radiesse .” “Her Botox is so overdone she's lost her expression… the mouth area looks frozen. The sheen to her skin is likely from laser treatments such as CO2 laser which would result in this artificial ..
Authors: Alibardi L, Polazzi E Abstract The present study shows the localization of epidermal and dermal proteins produced in lizard skin cultivated in vitro. Cells from the skin have been cultured for up to one month to detect the expression of keratins, actin, vimentin and extracellular matrix proteins (fibronectin, chondroitin sulphate proteoglycan, elastin and collagen I). Keratinocytes and dermal cells weakly immunoreact for Pan-Cytokeratin but not with the K17-antibody at the beginning of the cell culture when numerous keratin bundles are present in keratinocyte cytoplasm.
AbstractWe have investigated the expression and role of galectin‐1 and other galectins in psoriasis and in the Th1/Th17 effector and dendritic cell responses associated with this chronic inflammatory skin condition.
In this study, we examined the role of periostin in the process of cutaneous wound repair using periostin‐deficient mice and by analyzing the effects of periostin on dermal fibroblasts.
Authors: Du J, Zeng C, Li Q, Chen B, Liu H, Huang X, Huang Q Abstract Sphingosine-1-phosphate (S1P) is a bioactive sophospholipid with various S1P receptor (S1PR) expression profiles in cells of different origin. S1PR1, R3 and – to a lesser extent – R2 were the main receptors expressed in most of endothelial cells (ECs).
Exp Clin Endocrinol DiabetesDOI: 10.1055/s-0031-1291298The hepatocytes from the adult mice when stimulated by glucose had been reported to synthesize and secrete insulin.
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